Author(s):
1. Gorana Nikolić, 2. Ivana Mileusnić, Serbia

Abstract:
Melanoma is the most malignant skin cancer in human population due to late detection, high invasiveness and rapid infiltration. Beside melanoma, skin cancer includes Basal cell cancer (BCC), Squamous cell cancer (SCC), and other rare cancers like Mercel cell carcinoma and Langerhans cell carcinoma. The annual increase of melanoma patients in Serbia is 6%, while this number varies in rest of the world between 5% and 7%. Various techniques are used for detection and differentiation of skin cancers that differ in principle of operation and detection efficiency. A novel method is an opto-magnetic imaging spectroscopy (OMIS) based on light-tissue interaction. In more details, this technique measures the difference between responses of the skin when it is illuminated with white or polarized light under normal incidence or at Brewster angle. Different skin responses could be also measured under fixed incident angle of the blue and the violet light. In this study, OMIS is used for detection and differentiation between simple mole (naevus) and melanoma, and for differentiation between non-melanoma cancer and melanoma. Investigations have included 65 patients with dermoscopic and histopathology confirmed different lesions. It is shown that good agreement between the results of the OMIS method and histopathological diagnosis were obtained in the sample covering 97% of the patients. This demonstrates that OMIS method could be one of the diagnostic methods for detection and differentiation of skin lesions.

Key words:
melanoma, OMIS, histopathology, dermoscopy

Thematic field:
SYMPOSIUM B: Biomaterials and nanomedicine

Date of abstract submission:
20.05.2013.

Number of visits:
242

Conference:
Contemporary Materials - 2013 - Savremeni materijali

Applied paper from author